Accelerating research

and development of

new antibiotics and



Centre for Antimicrobial Research

Centre for Antimicrobial Research (CARES) is a Dutch research initiative for antimicrobials research, focusing on the development of novel antibiotics and antimicrobials. The CARES programme aims at delivering novel lead compounds to refill the antibiotic pipelines. An aim in itself is to build a strong collaborative network consisting of universities, university medical centres and companies.

CARES believes it is vital that the public and private sector jointly take up responsibility to develop new antibiotics and to ensure a continuous supply of novel candidate drugs into clinical trials. CARES focuses on the development of novel compounds and the translational science to bring these new antibiotics to the clinic.

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Centre for Sustainable Antimicrobials

The Centre for Sustainable Antimicrobials (CeSAM) in Groningen comprises creative fundamental research, including advanced facilities for high-throughput (animal) testing and adequate patient-screening. CeSAM’s goal lies in interdisciplinary basic and translational research to develop novel antibiotics and therapeutic (‘theragnostic’) concepts to fight resistant bacterial strains, simultaneously allowing sustainable prevention of resistance development and spreading.

The scientific challenge is to develop novel intelligent antimicrobials to combat resistant pathogens, which will be pursued throughout the production pipeline to complete phase I clinical trials. The clinical challenge is to develop innovative solutions for personalized on-demand theragnostic strategies based on existing and novel antibiotics to optimize treatment and to prevent both health care-associated infections due to antimicrobial resistance and spreading of resistant strains.

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Netherlands Centre for One Health

The Netherlands Centre for One Health (NCOH) brings together world-leading academic research institutes in the Netherlands active in various complementary fields of One Health together with other leading parties. Thereby, it forges an open innovation network to take joint responsibility for finding answers to global One Health challenges. The NCOH primarily aims for an integrated approach to tackle the global risk of infectious diseases by considering human, animal, wildlife, and ecosystem health. This virtual science-driven institution focuses its research and increase of knowledge along four major Strategic Research Themes related to infectious diseases: Tackling Antibiotic Resistance (NCOH-AMR), Emerging Infectious Diseases Preparedness (NCOH-EID), Smart and Healthy Farming (NCOH-SHF), and Healthy Wildlife and Ecosystems (NCOH-HWE). The NADP is strategically and organisationally embedded within NCOH-AMR.

The strategic theme NCOH-AMR aims to decrease the morbidity and mortality of antibiotic-resistant bacterial infections in humans through use-inspired, excellent, fundamental, translational, and applied One Health research on antimicrobial resistance. The NCOH-AMR, as other NCOH themes, is organised through so-called Solution Sets. Within NCOH-AMR, the NADP will provide a platform for public-private partnerships in the Solution Sets “New Antibiotics” and “New Alternatives”.

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